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Statin side effects: Weigh the benefits and risks

How to relieve statin side effects

To relieve side effects believed to be caused by statins, your doctor may recommend several options. Discuss these steps with your doctor before trying them:

  • Take a brief break from statin therapy. Sometimes it's hard to tell whether the muscle aches or other problems you're having are statin side effects or just part of the aging process. Taking a break can help you determine whether your aches and pains are due to statins instead of something else.
  • Switch to another statin drug. It's possible, although unlikely, that one particular statin may cause side effects for you while another statin won't. It's thought that simvastatin (Zocor) may be more likely to cause muscle pain as a side effect than other statins when it's taken at high doses.
  • Change your dose. Lowering your dose may reduce some of your side effects, but it may also reduce some of the cholesterol-lowering benefits your medication has. Another option is to take the medication every other day, especially if you take a statin that stays in the blood for several days. Talk to your doctor to determine if this is appropriate for you.
  • Take it easy when exercising. Unaccustomed vigorous exercise might increase the risk of muscle injury. It's best to make changes in your exercise routine more gradually. Exercise causes muscle pain too, so it is sometimes difficult to know if the pain comes from the statin or the exercise in someone who just started an exercise program.
  • Consider other cholesterol-lowering medications. Although statins are the most effective oral medications for lowering your cholesterol, other types of drugs also are available. Sometimes, taking a combination of cholesterol drugs can provide the same result with lower doses of statins.
  • Try coenzyme Q10 supplements. Coenzyme Q10 supplements may help prevent statin side effects in some people, though more studies are needed to determine any benefits of taking it. Talk to your doctor first to make sure the supplement won't interact with any of your other medications.